Almighty God hath not bestowed on mankind a remedy of so universal an extent and so efficacious in curing divers maladies as opiates.

Deum Omnipotentum, non aliud remedium, quod vel pluribus malis debellandis par fit, vel leadem effecaciús extirpet, humano generi, in miferiarum solamen, concessisse, quam funt Opiata.

Thomas Sydenham

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Sydenham, Thomas. Observationes Medicae. London, 1676.